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id="picBox" class="picBox"> <ul class="cf"> <li><a class="proimg" target="_blank"><img src="http://img74.chem17.com/gxhpic_ee1d6a233c/99c876c5d9ae48d98baa768a1c87deb58c94abfd76ffa7fec1386c40bbf1e65548c53b8da33fa639_300_300_5.jpg"/></a></li> </ul> </div> <div class="retnyx88dwww" id="listBox" class="listBox"> <ul class="cf"> <li id="retnyx88dwww" class="on"><span id="retnyx88dwww" class="xtimg"><img src="http://img74.chem17.com/gxhpic_ee1d6a233c/99c876c5d9ae48d98baa768a1c87deb58c94abfd76ffa7fec1386c40bbf1e65548c53b8da33fa639_70_70_5.jpg" /></span></li> </ul> </div> </div> </div> <div id="retnyx88dwww" class="ny_pro_right"> <h1 class="pro_name">戈舍瑞林</h1> <p class="jyms_con">胺碘酮鹽酸鹽雜質(zhì)E;高舍瑞林;戈舍瑞林;果絲瑞寧;性瑞林;3-[焦谷氨酰組氨酰色氨酰絲氨酰醋氨酰(3-O-叔丁基)-D絲氨酰亮氨酰精氨酰脯氨酰]肼基甲酰胺;戈舍瑞林-D5;戈舍瑞林中間體</p> <p class="cpxh">產(chǎn)品型號(hào)：CAS: 65807-02-5</p> <p class="gxsj">更新時(shí)間：2024-06-20</p> <div id="retnyx88dwww" class="pro_btn"> <a href="#nr_textbox" class="zxxj">在線詢價(jià)</a> <a href="/contact.html" class="lxwm">聯(lián)系我們</a> </div> </div> </div>  <div class="retnyx88dwww" id="ny_pro_box02"> <div class="retnyx88dwww" id="con"> <ul id="tags"> <li id="retnyx88dwww" class="selectTag"><a onmouseover="selectTag('tagContent0',this)" href="javascript:void(0)" onfocus="this.blur()">詳細(xì)介紹</a></li> </ul> <div class="retnyx88dwww" id="tagContent"> <div id="retnyx88dwww" class="tagContent selectTag" id="tagContent0" style="display: block;"><div id="retnyx88dwww" class="tabledivclass" style="width: 99%; height: 349px;"><table border="0" cellspacing="1" align="left" width="556" style="max-width: 748px;"><tbody><tr class="firstRow"><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px"><span style="font-family:宋體">中文名稱</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體"><strong>戈舍瑞林</strong></span></span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;font-size:14px"><span style="font-family:宋體">中文同義詞</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體">胺碘酮鹽酸鹽雜質(zhì)</span><span style="font-family:Arial">E</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體">高舍瑞林</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體"><strong>戈舍瑞林</strong></span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體">果絲瑞寧</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體">性瑞林</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px">3-[<span style="font-family:宋體">焦谷氨酰組氨酰色氨酰絲氨酰醋氨酰</span><span style="font-family:Arial">(3-O-</span><span style="font-family:宋體">叔丁基</span><span style="font-family:Arial">)-D</span><span style="font-family:宋體">絲氨酰亮氨酰精氨酰脯氨酰</span><span style="font-family:Arial">]</span><span style="font-family:宋體">肼基甲酰胺</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體"><strong>戈舍瑞林</strong></span><span style="font-family:Arial">-D5</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,102,204);font-size:14px"><span style="font-family:宋體"><strong>戈舍瑞林</strong>中間體</span></span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px"><span style="font-family:宋體">英文名稱</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;font-size:14px">Goserelin</span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;font-size:14px"><span style="font-family:宋體">英文同義詞</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><br/></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px">CAS<span style="font-family:宋體">號(hào)</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><strong><span style="font-family:Arial;font-size:14px">65807-02-5</span></strong></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;font-size:14px"><span style="font-family:宋體">分子式</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;font-size:14px">C61H88N18O16</span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px"><span style="font-family:宋體">分子量</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;font-size:14px">1329.46</span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><p><span style="font-family:Arial;font-size:14px">EINECS<span style="font-family:宋體">號(hào)</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(255, 255, 255);"><br/></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px"><span style="font-family:宋體">相關(guān)類別</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體">抗代謝物抗腫瘤藥物</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體">抗腫瘤藥</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體">藥物</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px">Pepetides</span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px">peptides</span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px">hormones</span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體">醫(yī)藥原料</span></span><span style="font-family:Arial;font-size:14px">;</span><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px"><span style="font-family:宋體">生物制藥</span></span></p></td></tr><tr><td width="48" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(84,84,84);font-size:14px">Mol<span style="font-family:宋體">文件</span><span style="font-family:Arial">:</span></span></p></td><td width="508" valign="center" style="padding: 0px; border-width: initial; border-style: none; border-color: initial; background: rgb(250, 250, 250);"><p><span style="font-family:Arial;color:rgb(0,51,153);font-size:14px">65807-02-5.mol</span></p></td></tr></tbody></table></div><p><span style=";font-family:Arial;color:rgb(0,102,204);font-size:14px">0.2mmol 5-oxoPro-His-NHNH2<span style="font-family:宋體">懸浮于</span><span style="font-family:Arial">0.9ml</span><span style="font-family:宋體">二甲基甲酰胺和</span><span style="font-family:Arial">0.7ml</span><span style="font-family:宋體">二甲亞砜的混合溶劑中，在</span><span style="font-family:Arial">0℃</span><span style="font-family:宋體">和攪拌下，加入</span><span style="font-family:Arial">0.8mmol 5.7mol/L</span><span style="font-family:宋體">鹽酸的二氧六環(huán)溶液，劇烈攪拌</span><span style="font-family:Arial">5min</span><span style="font-family:宋體">，得到澄清的溶液。冷至</span><span style="font-family:Arial">-20℃</span><span style="font-family:宋體">，加入</span><span style="font-family:Arial">0.22mmol</span><span style="font-family:宋體">亞硝酸叔丁酯，再攪拌</span><span style="font-family:Arial">25min</span><span style="font-family:宋體">。冷至</span><span style="font-family:Arial">-30℃</span><span style="font-family:宋體">，加入</span><span style="font-family:Arial">0.8mmol</span><span style="font-family:宋體">三乙胺來(lái)中和。加人冷至</span><span style="font-family:Arial">-20℃</span><span style="font-family:宋體">的</span><span style="font-family:Arial">0.1mmol</span><span style="font-family:宋體">的</span><span style="font-family:Arial">L-Trp-Ser-Tyr-D-Ser(t-Bu)-Leu-Arg-PrcrNHNHCONH2</span>和<span style="font-family:Arial">0.1mmol</span><span style="font-family:宋體">三乙胺溶于</span><span style="font-family:Arial">lml</span><span style="font-family:宋體">二甲基甲酰胺的溶液，然后在</span><span style="font-family:Arial">4℃</span><span style="font-family:宋體">下攪拌</span><span style="font-family:Arial">24h</span><span style="font-family:宋體">。減壓蒸出溶劑，剩余物用</span><span style="font-family:Arial">Sephadex LH-20</span><span style="font-family:宋體">進(jìn)行柱層析，用二甲基甲酰胺洗脫。然后用</span><span style="font-family:Arial">SephadexG-25</span><span style="font-family:宋體">來(lái)提純，用正丁醇：乙酸：水：吡啶</span><span 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